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在摄入后最初48小时内,帕氏布鲁线虫微丝蚴在骚扰阿蚊体内的命运。

The fate of Brugia pahangi microfilariae in Armigeres subalbatus during the first 48 hours post ingestion.

作者信息

Zahedi M

机构信息

Dept. Parasitology, Medical Faculty UKM, Kuala Lumpur, Malaysia.

出版信息

Trop Med Parasitol. 1994 Mar;45(1):33-5.

PMID:7915044
Abstract

In Armigeres subalbatus, 60% and 3% of the ingested Brugia pahangi microfilariae (mf) respectively migrated into the haemocoel and the thorax within 5 minutes post ingestion (p.i.). Most of the mf had migrated from the gut into the haemocoel within the first 10 minutes p.i. There was no correlation between the number of mf ingested and the migration rate though those in mosquitoes with a low mf burden tend to migrate earlier. At 24 hours p.i., 5-30% of the mf were still in the gut; 19% of these mf were immobile. At 48 hours p.i. only 2% of the mf were mobile. B. pahangi mf isolated from blood meals at 24 hours p.i., failed to develop when inoculated into Armigeres subalbatus. 54% and 73% of the mf isolated from a 24 hour old clotted blood of a B. pahangi-infected cat and fresh peripheral cat blood respectively developed into stage-1 larva. Probably mf left in the midgut at 24 hours p.i. are the young and immature worms and are physiologically incapable of penetrating the gut.

摘要

在骚扰阿蚊中,分别有60%和3%摄入的彭亨丝虫微丝蚴(mf)在摄入后5分钟内迁移到血腔和胸部。大多数微丝蚴在摄入后的前10分钟内从肠道迁移到血腔。摄入的微丝蚴数量与迁移率之间没有相关性,尽管微丝蚴负荷低的蚊子中的微丝蚴往往迁移得更早。摄入后24小时,5%-30%的微丝蚴仍在肠道中;这些微丝蚴中有19%不活动。摄入后48小时,只有2%的微丝蚴可活动。摄入后24小时从血餐中分离出的彭亨丝虫微丝蚴接种到骚扰阿蚊中后无法发育。分别从感染彭亨丝虫的猫24小时的凝血和新鲜外周猫血中分离出的微丝蚴,有54%和73%发育成1期幼虫。摄入后24小时留在中肠的微丝蚴可能是年轻和未成熟蠕虫,在生理上无法穿透肠道。

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