Niel G, Vernard P, Bruhnes J, Charmot G, Gentilini M
Bull Soc Pathol Exot Filiales. 1976 Jan-Feb;69(1):84-92.
An immunological study has complemented the epidemiological survey on Bancroft filariosis in the Mayotte island (Comores) carried out by BRUNHES et al., 1971. The search for antibodies to Dipatolonema viteae and Setaria labiotopapilosa was performed by means of electrophoresis and immunofluorescence in 87 individuals and 2 hydrocele fluids. Immunoelectrophoresis confirmed the high endemicity ratio: 57 o/o of the individuals presented 1 to 7 precipitating lines; with immunofluorescence 55 o/o of the subjects had a titer of 200 to 1.600. 46 to 50 o/o of the positivities were observed in people showing clinical symptoms without microfilaremia. On the other hand, 36 to 48 o/o of the proved filarian cases yielded negative results with immunofluorescence or electrophoresis. These figures emphasize the significance and insufficiencies of immunologic techniques for the diagnostic of bancroftoses. In spite of the frequency of certain well identified precipitating systems, an immunoelectrophoretic analysis did not allow to demonstrate a constant and characteristic scheme.
一项免疫学研究补充了BRUNHES等人于1971年在马约特岛（科摩罗）进行的班氏丝虫病流行病学调查。通过电泳和免疫荧光法，对87名个体和2份鞘膜积液进行了对魏氏棘唇线虫和唇乳突丝状线虫抗体的检测。免疫电泳证实了高流行率：57%的个体出现1至7条沉淀线；通过免疫荧光法，55%的受试者滴度为200至1600。在有临床症状但无微丝蚴血症的人群中，46%至50%呈阳性。另一方面，经证实的丝虫病病例中有36%至48%通过免疫荧光或电泳得出阴性结果。这些数据强调了免疫技术在班氏丝虫病诊断中的意义和不足之处。尽管某些明确的沉淀系统出现频率较高，但免疫电泳分析仍无法证明有恒定且具特征性的模式。
