Chu N S
Department of Neurology, Chang Gung Medical College and Memorial Hospital, Taipei, Taiwan, R.O.C.
J Formos Med Assoc. 1994 Jan;93(1):56-60.
Blink reflex and brainstem auditory evoked potential (BAEP) were studied in 10 patients with Wilson's disease (WD) and 10 family members. In blink reflex, R1 and R2 latencies as well as R2 duration were prolonged in the patient group, but not in the family group. In BAEP, latencies of peaks III and V and interpeaks I-III, III-V and I-V were also delayed only in the patient group. These data suggest that blink reflex abnormalities in WD are different from other movement disorders and are mainly due to brainstem dysfunction.
对10例肝豆状核变性（WD）患者及10名家庭成员进行了瞬目反射和脑干听觉诱发电位（BAEP）研究。在瞬目反射中，患者组的R1和R2潜伏期以及R2时长延长，而家族组未出现这种情况。在BAEP中，仅患者组的峰III和峰V潜伏期以及峰间期I - III、III - V和I - V延迟。这些数据表明，WD中的瞬目反射异常与其他运动障碍不同，主要是由于脑干功能障碍所致。
