Orkin M, Maibach H I
Pediatr Clin North Am. 1978 May;25(2):371-86. doi: 10.1016/s0031-3955(16)33573-8.
We are in the midst of a pandemic of scabies. Classic scabies is seen less frequently in the current cycle. The infestation frequently occurs in special forms, the differential diagnosis of which includes nearly every pruritic dermatosis. The cause of the current pandemic is not clear but there is evidence that immunologic factors, particularly delayed hypersensitivity, play a principal role. The diagnosis should be made with certainty, preferably by identifying the mite prior to instituting therapy. The modern scabicides are highly effective. A recent re-evaluation of the risk-benefit relationships of lindane has led to altered therapeutic routines.
我们正处于疥疮大流行之中。在当前流行周期中，典型疥疮的出现频率较低。感染常以特殊形式发生，其鉴别诊断几乎涵盖了每一种瘙痒性皮肤病。目前这场大流行的病因尚不清楚，但有证据表明免疫因素，尤其是迟发型超敏反应，起着主要作用。诊断应确切无误，最好在开始治疗前找到疥螨。现代杀疥剂非常有效。最近对林丹风险效益关系的重新评估导致了治疗方案的改变。
