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编码与酵母核糖体蛋白S31同源的蛋白质的盘基网柄菌基因的核苷酸序列。

Nucleotide sequence of a Dictyostelium discoideum gene encoding a protein homologous to the yeast ribosomal protein S31.

作者信息

Hoja U, Hofmann J, Marschalek R, Dingermann T

机构信息

Institut für Biochemie, Med. Fak., Universität Erlangen-Nürnberg, Germany.

出版信息

Biochem Biophys Res Commun. 1993 Jan 15;190(1):134-9. doi: 10.1006/bbrc.1993.1021.

Abstract

A cDNA clone has been isolated whose coding potential is significantly homologous to the yeast ribosomal protein S31. The single copy genomic gene contains a 271 bp intron immediately downstream from the ATG translation initiation codon and is flanked by cannonical exon/intron junctions. The intron carries a CAATCAAT motif which has been described as inducer element for discoidin I gamma expression and which has also been found within the intron of the rp29 gene form D. discoideum. The deduced protein contains 110 amino acids and is slightly basic.

摘要

已分离出一个cDNA克隆,其编码潜能与酵母核糖体蛋白S31具有显著同源性。单拷贝基因组基因在ATG翻译起始密码子下游紧邻处含有一个271 bp的内含子,两侧为典型的外显子/内含子连接。该内含子带有一个CAATCAAT基序,该基序已被描述为盘状蛋白Iγ表达的诱导元件,并且也在盘基网柄菌rp29基因的内含子中发现。推导的蛋白质含有110个氨基酸,呈弱碱性。

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