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编码圆斑蝰蛇毒中血小板聚集抑制剂和出血蛋白共同前体的全长cDNA的核苷酸序列。

Nucleotide sequence of a full-length cDNA encoding a common precursor of platelet aggregation inhibitor and hemorrhagic protein from Calloselasma rhodostoma venom.

作者信息

Au L C, Chou J S, Chang K J, Teh G W, Lin S B

机构信息

Department of Medical Research, Veterans General Hospital-Taipei, Taiwan, ROC.

出版信息

Biochim Biophys Acta. 1993 May 28;1173(2):243-5. doi: 10.1016/0167-4781(93)90190-o.

Abstract

The nucleotide sequence of a full-length cDNA encoding the common precursor of a platelet aggregation inhibitor, rhodostomin and a hemorrhagic protein from Calloselasma rhodostoma snake venom is presented. The 1.98-kb cDNA contains an open reading frame encoding 478 amino acid residues. The complete structure of the precursor protein encoded by the cDNA is elucidated.

摘要

本文给出了编码血小板聚集抑制剂罗豆素和红口蝮蛇毒出血蛋白共同前体的全长cDNA的核苷酸序列。该1.98kb的cDNA包含一个编码478个氨基酸残基的开放阅读框。阐明了由该cDNA编码的前体蛋白的完整结构。

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