Trufakin V A, Madar J, Matousek V, Hraba T
Folia Biol (Praha). 1976;22(5):298-303.
Direct PFC to SRBC were enumerated simultaneously by the LHL and LHG in the spleens of partially tolerant and control rats. The sensitivity of LHL was higher than that of LHG, but the factor by which the number of PFC was higher in LHL than in LHG was in the two groups similar (1.44 in tolerant and 1.47 in control group). When the plaque size distribution was studied in the LHL, a significant increase in small size plaques was observed in tolerant rats. The findings are discussed and the conclusion is reached that the decrease in AFC number and not in antibody production by individual PFC is the main factor responsible for partial tolerance.
通过局部耐受大鼠和对照大鼠脾脏中的LHL和LHG同时对直接针对绵羊红细胞（SRBC）的脾集落形成细胞（PFC）进行计数。LHL的敏感性高于LHG，但LHL中PFC数量高于LHG的倍数在两组中相似（耐受组为1.44，对照组为1.47）。当研究LHL中的噬斑大小分布时，在耐受大鼠中观察到小尺寸噬斑显著增加。对这些发现进行了讨论，并得出结论：AFC数量的减少而非单个PFC抗体产生的减少是导致局部耐受的主要因素。
