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耳部和背部皮肤弱不相容同种异体移植不同存活率的分析。

Analysis of different survival of weakly incompatible allografts of skin from the ear and back.

作者信息

Polácková M, Viklický V

出版信息

Folia Biol (Praha). 1976;22(5):363-5.

PMID:791693
Abstract

A comparison of the survival of skin grafts across the H-barrier presented by the male-specific antigen in mice was made with grafts of skin from different sources, namely from the back or from the ear. Their survival was roughly similar provided the ear skin was depleted of the subepidermal connective tissue with the cartilage. With this layer intact, the ear skin grafts had a prolonged survival and some of them even took permanently. A local administration of a mucolytic agent to the normal grafts from the back accelerated their rejection. The factors of the subepidermal connective tissue which might be responsible for the effect on the survival of weakly incompatible skin grafts and in this connection the role of the source of the skin are discussed.

摘要

将来自不同来源(即背部或耳部)的皮肤移植到小鼠体内,与跨越雄性特异性抗原所呈现的H屏障的皮肤移植的存活情况进行了比较。如果耳部皮肤的皮下结缔组织和软骨被去除,它们的存活情况大致相似。在这层保持完整的情况下,耳部皮肤移植的存活时间延长,其中一些甚至永久存活。对来自背部的正常移植皮肤局部施用黏液溶解剂会加速其排斥反应。讨论了皮下结缔组织中可能影响弱不相容皮肤移植存活的因素,以及在此方面皮肤来源的作用。

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