Stewart M G, Schwartz M R, Alford B R
Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, Tex.
Arch Otolaryngol Head Neck Surg. 1994 Oct;120(10):1151-5. doi: 10.1001/archotol.1994.01880340091016.
Although liposarcoma is the second most common soft-tissue sarcoma in adults, the incidence of liposarcoma of the head and neck is low. There are only 83 reported cases of head and neck liposarcoma. We report four cases of atypical and malignant lipomatous lesions of the head and neck and discuss their histologic classification and treatment implications. The histologic nature of liposarcoma is correlated clinically with treatment outcome. Recently, many authors have adopted the term atypical lipoma to describe well-differentiated lipomatous lesions in superficial extremity locations because of their tendency toward local recurrence only, without metastases or patient mortality. Although we accept the classification atypical lipoma for superficial, well-differentiated lesions, we believe that histologically similar lesions in nonsuperficial locations in the head and neck are best designated "well-differentiated liposarcoma."
尽管脂肪肉瘤是成人中第二常见的软组织肉瘤，但头颈部脂肪肉瘤的发病率较低。头颈部脂肪肉瘤仅有83例报道病例。我们报告4例头颈部非典型性和恶性脂肪瘤样病变，并讨论其组织学分类及治疗意义。脂肪肉瘤的组织学性质与临床治疗结果相关。近来，许多作者采用“非典型脂肪瘤”这一术语来描述四肢浅表部位分化良好的脂肪瘤样病变，因为它们仅倾向于局部复发，无转移或患者死亡情况。尽管我们认可将非典型脂肪瘤用于浅表、分化良好的病变，但我们认为头颈部非浅表部位组织学上类似的病变最好命名为“高分化脂肪肉瘤”。
