Newman A
MRC Laboratory of Molecular Biology, Cambridge, UK.
Curr Opin Cell Biol. 1994 Jun;6(3):360-7. doi: 10.1016/0955-0674(94)90027-2.
Genetic and biochemical studies have recently shown that the splice sites in nuclear pre-mRNAs are aligned for the transesterification reactions through a collaboration between U5 and U6 small nuclear RNAs, which form the heart of a network of RNA-based interactions in the active spliceosome.