一种与T细胞非霍奇金淋巴瘤相关的骨髓增殖性疾病中的t(8;13)(p11;q12)易位。
t(8;13) (p11;q12) translocation in a myeloproliferative disorder associated with a T-cell non-Hodgkin lymphoma.
作者信息
Leslie J, Barker T, Glancy M, Jennings B, Pearson J
机构信息
Department of Haematology, Norfolk and Norwich Hospital.
出版信息
Br J Haematol. 1994 Apr;86(4):876-8. doi: 10.1111/j.1365-2141.1994.tb04847.x.
Abstract
An unusual cytogenetic translocation, t(8;13) (p11;q12), is described in a patient presenting with a CML-like myeloproliferative disorder associated with a high-grade T-cell lymphoma. Evidence is presented suggesting that the breakpoint region in the translocation involves a site implicated in both the T cell malignancy and the abnormal granulocyte proliferation.
摘要
在一名患有与高级别T细胞淋巴瘤相关的慢性粒细胞白血病样骨髓增殖性疾病的患者中，发现了一种不寻常的细胞遗传学易位，即t(8;13) (p11;q12)。有证据表明，该易位中的断点区域涉及一个与T细胞恶性肿瘤和异常粒细胞增殖均相关的位点。
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