Hayman G T, Miernyk J A
Phytoproducts Research Unit, National Center for Agricultural Utilization Research, Peoria, IL 61604.
Biochim Biophys Acta. 1994 Oct 18;1219(2):536-8. doi: 10.1016/0167-4781(94)90083-3.
The nucleotide sequence of a cDNA clone from Arabidopsis thaliana ecotype Columbia was determined, and the corresponding amino acid sequence deduced. The predicted sequence is highly homologous to those of members of the cyclophilin A-family of peptidyl-prolyl cis-trans isomerases. The tryptophan residue necessary for interaction with cyclosporin A is located at approximately the same position in the plant sequence as it is in mammalian sequences. The carboxy-terminus of the plant prolyl isomerase sequence contains a cryptic prenylation motif.
