Shoemaker M, Hannaford B
Department of Electrical Engineering, Seattle Pacific University, WA 98119.
Biol Cybern. 1994;71(3):251-62. doi: 10.1007/BF00202764.
This study sought to investigate the role of the Renshaw cell with respect to transient motoneuron firing. By studying the cat motoneuron and Renshaw cell, several low-order lumped parameter models were developed that simulate the known characteristics of the injected input current vs. firing rate. The neuron models in the Renshaw cell inhibition configuration were tuned to fit experimental data from cat motoneurons. Models included both linear versions and those with sigmoidal nonlinearities. Results of the simulation indicate that the motoneuron itself provides the adaptation seen in its firing rate and that the Renshaw cell's role is primarily to fine-tune the motoneuron's adaptation process.
本研究旨在探讨闰绍细胞在瞬态运动神经元放电方面的作用。通过研究猫的运动神经元和闰绍细胞，开发了几个低阶集总参数模型，这些模型模拟了注入输入电流与放电率的已知特征。处于闰绍细胞抑制配置的神经元模型经过调整以拟合来自猫运动神经元的实验数据。模型包括线性版本和具有S形非线性的版本。模拟结果表明，运动神经元自身产生了其放电率中所见的适应性，而闰绍细胞的作用主要是对运动神经元的适应过程进行微调。
