Shields M B, McCoy R C, Shelburne J D
Invest Ophthalmol. 1976 Dec;15(12):1014-7.
The trabecular meshwork of eyes with open-angle glaucoma has been demonstrated to have an increase in gamma globulin and plasma cells, raising the question of an immunogenic mechanism in this disorder. In the present study, however, immunofluorescence assays on the trabecular meshwork of eyes with open-angle glaucoma were negative for specific immunoglobulins and for complement components that would result specifically from an antigen-antibody reaction. The study fails to provide any evidence in support of an immunogenic mechanism in open-angle glaucoma.
开角型青光眼患者眼睛的小梁网已被证明存在γ球蛋白和浆细胞增多的情况，这引发了该疾病中免疫原性机制的问题。然而，在本研究中，对开角型青光眼患者眼睛的小梁网进行的免疫荧光测定，针对特定免疫球蛋白和补体成分呈阴性，而这些成分是抗原 - 抗体反应的特异性结果。该研究未能提供任何证据支持开角型青光眼存在免疫原性机制。
