[The association between arterial hypertension, obesity and hypercholesterolemia in a sample of the adult population of Catalonia].

BACKGROUND

The Framingham's study has demonstrated that the incidence of cardiovascular diseases increases when several risk factors are present. In this study, the association between the main cardiovascular risk factors has been studied in a random sample from the adult population of Catalonia.

METHODS

A random sample was obtained (n = 314) from the adult population of Catalonia and univariate and multivariate statistical procedures were used to analyze the association between the following risk factors: HDL, hypertriglyceridemia, obesity, diabetes and tobacco consumption.

RESULTS

A simple correlation was observed between most of the risk factors. The multiple linear regression analysis showed that both the diastolic and systolic arterial pressures were correlated with total levels of cholesterol, body mass index and age (r = 0.65 for SAP and r = 0.48 for DAP); levels of total cholesterol were correlated with levels of triglycerides and age (r = 0.57); levels of triglycerides were correlated with levels of total cholesterol and cholesterol-HDL, body mass index and age (r = 0.61); body mass index was correlated with levels of triglycerides, total cholesterol, cholesterol-HDL and age (r = 0.52) (p < 0.001). The prevalence of hypercholesterolemia, obesity and diabetes was higher and the prevalence of tobacco consumption was lower among the hypertensives (SAP > 140 and/or DAP > 90 mm Hg) than among normotensives, being the odds ratio 3.56 (2-6.33) for hypercholesterolemia; 3.65 (1.66-8.09) for obesity; 3.70 (1.06-13.45) for diabetes and 0.40 (0.22-0.72) for tobacco consumption. The adjusted odds ratio derived from multiple logistic regression analysis was 2.52 (1.38-4.64) for hypercholesterolemia; 2.40 (1.05-5.46) for obesity, 1.74 (0.50-6.04) for diabetes and 0.63 (0.33-1.20) for tobacco consumption, being statistically significant in the case of hypercholesterolemia (p = 0.002) and obesity (p = 0.038).

CONCLUSION

We have observed an association between the cardiovascular risk factors analyzed. This association may be attributed to several physiological mechanisms and life-styles, which may influence the development of atherosclerosis and increase the cardiovascular risk.