Weig M, Harmsen D, Heesemann J
Institut für Hygiene und Mikrobiologie, Universität Würzburg.
Gesundheitswesen. 1994 Jul;56(7):380-2.
The ability to secrete a potent protein-toxin called diphtheria toxin (DT) is of outstanding importance for the outcome of diphtheria epidemics. Rapid molecular-biological screening methods are shown that can improve the differentiation between toxinogenic and non-toxinogenic Corynebacterium diphtheriae strains. The recently reported infection with an endemic, putative toxinogenic Corynebacterium diphtheriae strain in Lower Saxony is discussed.
分泌一种名为白喉毒素(DT)的强效蛋白质毒素的能力对于白喉疫情的结果至关重要。研究表明,快速分子生物学筛选方法可以改善产毒型和非产毒型白喉棒状杆菌菌株之间的鉴别。文中还讨论了最近报道的在下萨克森州感染一种地方性、假定产毒的白喉棒状杆菌菌株的情况。