Yu C H, Lin K H, Lin D T, Chen R L, Horng Y C, Chang M H
Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
J Formos Med Assoc. 1994 May;93(5):441-4.
Pancreatitis following the administration of L-asparaginase (L-asp) has been well documented. However, the progression of such pancreatitis to pseudocyst formation in some patients has been rarely reported. The few reported cases have been teenagers, with the exception of one adult. All pseudocysts required surgical management. This report documents a pancreatic pseudocyst in a seven-year-old girl with acute lymphoblastic leukemia whose treatment regimen included L-asp. The pseudocyst was managed medically with nasogastric decompression, intravenous hyperalimentation, and antibiotics. The pseudocyst resolved spontaneously in one month without complication.
使用L-天冬酰胺酶（L-asp）后发生胰腺炎已有充分文献记载。然而，在一些患者中，这种胰腺炎进展为假性囊肿形成的情况却鲜有报道。少数已报道的病例为青少年，仅有一例成年患者。所有假性囊肿均需手术治疗。本报告记录了一名患有急性淋巴细胞白血病的7岁女孩发生胰腺假性囊肿的病例，其治疗方案包括使用L-asp。该假性囊肿通过鼻胃减压、静脉高营养和抗生素进行内科治疗。假性囊肿在1个月内自行消退，未出现并发症。
