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神经性厌食症急性发作及体重恢复患者与健康年轻女性的静息代谢率和总能量消耗

Resting metabolic rate and total energy expenditure in acute and weight recovered patients with anorexia nervosa and in healthy young women.

作者信息

Platte P, Pirke K M, Trimborn P, Pietsch K, Krieg J C, Fichter M M

机构信息

Department of Psychoendocrinology, University of Trier, Germany.

出版信息

Int J Eat Disord. 1994 Jul;16(1):45-52. doi: 10.1002/1098-108x(199407)16:1<45::aid-eat2260160104>3.0.co;2-z.

DOI:10.1002/1098-108x(199407)16:1<45::aid-eat2260160104>3.0.co;2-z
PMID:7920580
Abstract

Because little is known about energy requirements in anorectic patients before and after weight gain we measured resting metabolic rate (RMR) by indirect calorimetry and total energy expenditure (TEE) by the doubly labeled water method in 6 patients with anorexia nervosa (body mass index [BMI] = 15.1 +/- 1.3 kg/m2), in 6 weight-recovered anorectics (BMI = 21.2 +/- 2.1 kg/m2), and in 12 healthy age-matched women (BMI = 20.5 +/- 1.9 kg/m2). No significant differences were found between the weight-recovered anorectic women and the healthy controls in RMR (1,330 +/- 131 kcal/day [weight-recovered]; 1,419 +/- 197 [controls]) and in TEE (2,602 +/- 637 kcal/day [weight-recovered]; 2,596 +/- 493 kcal/day [controls]). The RMR was significantly lower in the acutely ill anorectic patients (1,171 +/- 113 kcal/24 hr) than in weight-recovered anorectics and in healthy controls. The TEE was significantly lower in the anorectic group (1,946 +/- 192 kcal/day) than in the healthy controls.

摘要

由于对神经性厌食症患者体重增加前后的能量需求了解甚少,我们采用间接测热法测量了6例神经性厌食症患者(体重指数[BMI]=15.1±1.3kg/m²)、6例体重恢复的厌食症患者(BMI=21.2±2.1kg/m²)和12例年龄匹配的健康女性(BMI=20.5±1.9kg/m²)的静息代谢率(RMR),并采用双标记水法测量了总能量消耗(TEE)。体重恢复的厌食症女性与健康对照组在RMR(1330±131千卡/天[体重恢复者];1419±197[对照组])和TEE(2602±637千卡/天[体重恢复者];2596±493千卡/天[对照组])方面未发现显著差异。急性病厌食症患者的RMR(1171±113千卡/24小时)显著低于体重恢复的厌食症患者和健康对照组。厌食症组的TEE(1946±192千卡/天)显著低于健康对照组。

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