Francès C, Piette J C, Saada V, Papo T, Wechsler B, Chosidow O, Godeau P
Department of Internal Medicine, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Lupus. 1994 Apr;3(2):123-8. doi: 10.1177/096120339400300212.
Multiple subungual splinter hemorrhages have been initially described as an important sign of subacute endocarditis. Secondly, they were reported in various other conditions, especially in isolated cases of primary antiphospholipid syndrome. We report five patients with multiple fingernail subungual splinter hemorrhages occurring in the course of antiphospholipid syndrome. Antiphospholipid syndrome was secondary to systemic lupus erythematosus in two, to Fasciola hepatica infection in one and was considered as primary in two. In all patients multiple subungual splinter hemorrhages occurred concomitantly with thrombotic events of diverse arterial sites. The mechanism of subungual splinter hemorrhages is most probably thrombotic.
多发性甲下裂片形出血最初被描述为亚急性心内膜炎的一个重要体征。其次，在其他各种病症中也有报告，尤其是在原发性抗磷脂综合征的个别病例中。我们报告了5例在抗磷脂综合征病程中出现多发性指甲甲下裂片形出血的患者。抗磷脂综合征在2例中继发于系统性红斑狼疮，1例继发于肝片吸虫感染，2例被认为是原发性的。在所有患者中，多发性甲下裂片形出血均与不同动脉部位的血栓形成事件同时发生。甲下裂片形出血的机制很可能是血栓形成。
