de Mouzon J, Pouly J L, Le Vu B, Logert-Lebrun H, Bachelot A, Rufat P
Contracept Fertil Sex. 1993 May;21(5):358-61.
Ectopic pregnancies are more frequent among pregnancies resulting from assisted reproductive technology (ART) than in natural conceptions (6% to 7% vs 1%). Fivnat registry has allowed us to analyse 349 ectopics among 6049 clinical pregnancies collected from 1986 to 1990. Ectopic rate decreased with increasing women's age, and since 1986. The risk was also decreased in infertilities of non tubal origin, except for those of unknown origin in which it was at the same level than for tubal infertility. The risk was increased by 65% in stimulation regimens involving clomiphene citrate (CC). The observed decrease from 1986 to 1990 was strongly related to the decrease in use of CC.
与自然受孕（1%）相比，辅助生殖技术（ART）导致的妊娠中宫外孕更为常见（6%至7%对1%）。Fivnat登记处使我们能够分析1986年至1990年收集的6049例临床妊娠中的349例宫外孕。宫外孕发生率随女性年龄增加而降低，自1986年以来一直如此。非输卵管性不孕的风险也有所降低，但不明原因不孕的风险与输卵管性不孕处于同一水平。使用枸橼酸氯米芬（CC）的刺激方案会使风险增加65%。1986年至1990年观察到的下降与CC使用的减少密切相关。
