Logerot-Lebrun H, Nicollet B, de Mouzon J, Bachelot A, Pauchard M S, Rufat P
Contracept Fertil Sex. 1993 May;21(5):362-6.
FIVNAT registry collected 4,323 clinical pregnancies from 1987 to 1991, and allowed us to analyse the risk factors for multiple pregnancies. The multiple pregnancy rate is around 28%, 23% for twin pregnancies and 5% for triplet pregnancies. The number of transferred embryos is not the only factor to be significantly related with the risk of multiple pregnancy: male infertilities, cleavage rate over 50%, and women's age (at young ages multiple pregnancy rate are higher) are also significant. A multivariate logistic model was applied to analyse the relative part of these different factors. We also estimated the success rate and the multiple pregnancy rate which should have been obtained if the number of transferred embryos has been limited, in order to reduce the multiple pregnancy rate to 3%.
FIVNAT登记处收集了1987年至1991年期间的4323例临床妊娠数据，使我们能够分析多胎妊娠的风险因素。多胎妊娠率约为28%，其中双胎妊娠率为23%，三胎妊娠率为5%。移植胚胎的数量并非与多胎妊娠风险显著相关的唯一因素：男性不育、卵裂率超过50%以及女性年龄（年轻时多胎妊娠率较高）也具有显著性。应用多变量逻辑模型分析这些不同因素的相对作用。我们还估计了如果限制移植胚胎数量以将多胎妊娠率降至3%时应获得的成功率和多胎妊娠率。
