Monniaux D, Mariana J C, Cognié Y, Rabahi F, Monget P, Mermillod P, Baril G, Tomanek M, Pisselet C, Chupin D
Station INRA de Physiologie de la Reproduction des Mammifères Domestiques, URA CNRS 1291, Nouzilly.
Contracept Fertil Sex. 1993 May;21(5):403-7.
Terminal follicular maturation in the ovine and the bovine species involves growth and differentiation processes in follicles between 1-2 mm diameter and the preovulatory stage. During this maturation, the follicle acquires the ability to ovulate and the oocyte becomes able to be fertilized and to develop after fertilization. Selection of ovulatory follicles results from the integration of different parameters such as the circulating levels of gonadotropins, the structure of follicular populations and the sensitivity of the hypothalamo-pituitary axis to ovarian hormones. Differences between follicles for FSH and LH responsiveness can be amplified by paracrine intrafollicular regulations. These mechanisms are probably determinant for selection of ovulatory follicles.
绵羊和牛的卵泡终末成熟涉及直径在1-2毫米的卵泡至排卵前阶段的生长和分化过程。在这个成熟过程中，卵泡获得排卵能力，卵母细胞能够受精并在受精后发育。排卵卵泡的选择是由不同参数整合而成的，如促性腺激素的循环水平、卵泡群体的结构以及下丘脑-垂体轴对卵巢激素的敏感性。卵泡对促卵泡激素（FSH）和促黄体生成素（LH）反应性的差异可通过卵泡内旁分泌调节而放大。这些机制可能是排卵卵泡选择的决定性因素。
