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绵羊视交叉上核中芳香族L-氨基酸脱羧酶免疫组织化学。与酪氨酸羟化酶免疫组织化学的比较。

Aromatic L-amino acid decarboxylase immunohistochemistry in the suprachiasmatic nucleus of the sheep. Comparison with tyrosine hydroxylase immunohistochemistry.

作者信息

Tillet Y, Thibault J, Krieger M

机构信息

Laboratoire de Neuroendocrinologie Sexuelle, INRA, Nouzilly, France.

出版信息

Brain Res. 1994 Jun 20;648(2):319-23. doi: 10.1016/0006-8993(94)91134-7.

DOI:10.1016/0006-8993(94)91134-7
PMID:7922547
Abstract

Using antisera against tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AADC), we have demonstrated the presence of numerous AADC immunoreactive neurons and a few TH immunoreactive neurons, homogeneously distributed throughout the suprachiasmatic nucleus. Similar results have been described in other species. These observations show that this nucleus is able to synthesize trace amines (such as phenylethylamine or tyramine) in addition to dopamine. It is hypothesized that these trace amines are possibly involved in the integration of day length variation in sheep, a species whose reproduction is closely related to photoperiod.

摘要

利用抗酪氨酸羟化酶(TH)和芳香族L-氨基酸脱羧酶(AADC)的抗血清,我们已证明在整个视交叉上核中均匀分布着大量AADC免疫反应性神经元和少数TH免疫反应性神经元。在其他物种中也有类似的结果报道。这些观察结果表明,该核除了能合成多巴胺外,还能够合成痕量胺(如苯乙胺或酪胺)。据推测,这些痕量胺可能参与了绵羊日长变化的整合过程,绵羊是一种繁殖与光周期密切相关的物种。

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