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新型高强度甜味剂三氯蔗糖的开发与应用

The development and applications of sucralose, a new high-intensity sweetener.

作者信息

Knight I

机构信息

Redpath Specialty Products, Toronto, ON, Canada.

出版信息

Can J Physiol Pharmacol. 1994 Apr;72(4):435-9. doi: 10.1139/y94-063.

DOI:10.1139/y94-063
PMID:7922876
Abstract

Sucralose is a new sweetener discovered during a collaborative research program between Tate & Lyle and Queen Elizabeth College of the University of London. It is made by selective substitution of sucrose hydroxyl groups by chlorine, resulting in a highly intense (600x) sugarlike sweetness and exceptional stability at both high temperature and low pH. The research leading to the discovery of sweetness in differently halogenated sucrose is described, as well as the development of sucralose and the process of safety testing and government approval. Finally, sucralose properties and applications in Canada's food and beverage industries are discussed.

摘要

三氯蔗糖是在泰特利尔公司与伦敦大学伊丽莎白女王学院合作开展的一项研究项目中发现的一种新型甜味剂。它是通过用氯选择性取代蔗糖的羟基而制成的,具有极高的甜度(是蔗糖的600倍),并且在高温和低pH值条件下都具有出色的稳定性。文中描述了导致发现不同卤代蔗糖具有甜味的研究,以及三氯蔗糖的开发过程、安全性测试和政府审批流程。最后,讨论了三氯蔗糖在加拿大食品和饮料行业中的特性及应用。

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The development and applications of sucralose, a new high-intensity sweetener.新型高强度甜味剂三氯蔗糖的开发与应用
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Female rats show a bimodal preference response to the artificial sweetener sucralose.雌性大鼠对人工甜味剂三氯蔗糖表现出双峰偏好反应。
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No detriment in taste response or expression in offspring of mice fed representative levels of sucrose or non-caloric sucralose while pregnant.在孕期喂食代表性水平蔗糖或无热量三氯蔗糖的小鼠后代中,味觉反应或表达无损害。
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Effect of sucralose in coffee on plaque pH in human subjects.三氯蔗糖添加到咖啡中对人体受试者牙菌斑pH值的影响。
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Cross-over studies underestimate energy compensation: The example of sucrose-versus sucralose-containing drinks.交叉研究低估了能量补偿:以含蔗糖饮料与含三氯蔗糖饮料为例。
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Heating of food containing sucralose might result in the generation of potentially toxic chlorinated compounds.加热含有三氯蔗糖的食物可能会产生潜在有毒的氯化化合物。
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Effect of aqueous solutions of sucralose on plaque pH.
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