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腹主动脉局限性狭窄治疗中内膜切除术与血管成形术的比较

Endarterectomy versus angioplasty in the treatment of localized stenosis of the abdominal aorta.

作者信息

Steinmetz O K, McPhail N V, Hajjar G E, Barber G G, Cole C W

机构信息

Department of Surgery, Ottawa Civic Hospital, University of Ottawa, Ont.

出版信息

Can J Surg. 1994 Oct;37(5):385-90.

PMID:7922899
Abstract

OBJECTIVE

To compare the outcome after aortoiliac endarterectomy and percutaneous transluminal angioplasty (PTA) of the aorta for localized stenosis of the lower abdominal aorta.

DESIGN

Chart review of patients treated over a 5-year period.

SETTING

A university centre.

PATIENTS

Sixteen women, all of whom were smokers; 5 had hyperlipidemia, 4 had evidence of coronary artery disease, 3 were hypertensive, and 1 was diabetic.

INTERVENTIONS

Aortoiliac endarterectomy (eight women) and PTA (eight women).

MAIN OUTCOME MEASURES

Ankle-brachial pressure index (ABI), degree of claudication and clinical outcome.

RESULTS

Angiography showed localized stenosis of the lower aorta in all patients, aortic hypoplasia in nine patients and associated common iliac disease in seven. None of the eight patients managed by aortoiliac endarterectomy had complications or died. All were free of claudication at a mean follow-up of 29 months and had durable improvement in their ABI: mean ABI preoperatively was 0.69 (standard deviation [SD] 0.1) and postoperatively was 1.06 (SD 0.07). Of the eight patients treated by PTA, only one had partial dilatation; another had a subintimal tear with worsening symptoms and a fall in ABI, requiring surgery within 18 months. The remaining six were symptom free after a mean follow-up of 13.4 months. Aortic PTA resulted in improvement of the ABI: mean ABI before PTA was 0.69 (SD 0.19) and after PTA was 1.06 (SD 0.15).

CONCLUSIONS

Endarterectomy is a safe and effective method of treating occlusive disease limited to the distal aorta. PTA appears to be less reliable. However, it is recommended as the initial treatment of choice in patients with angiographically suitable lesions because it is less invasive.

摘要

目的

比较腹主动脉局限性狭窄行主髂动脉内膜切除术和经皮腔内血管成形术(PTA)后的疗效。

设计

对5年期间接受治疗的患者进行病历回顾。

地点

一所大学中心。

患者

16名女性,均为吸烟者;5例有高脂血症,4例有冠状动脉疾病证据,3例高血压,1例糖尿病。

干预措施

主髂动脉内膜切除术(8名女性)和PTA(8名女性)。

主要观察指标

踝臂压力指数(ABI)、跛行程度和临床疗效。

结果

血管造影显示所有患者腹主动脉局限性狭窄,9例主动脉发育不全,7例合并髂总动脉疾病。接受主髂动脉内膜切除术的8例患者均无并发症或死亡。平均随访29个月时,所有患者均无跛行,ABI持续改善:术前平均ABI为0.69(标准差[SD]0.1),术后为1.06(SD 0.07)。在接受PTA治疗的8例患者中,仅1例部分扩张;另1例出现内膜下撕裂,症状加重,ABI下降,需在18个月内手术。其余6例平均随访13.4个月后无症状。主动脉PTA使ABI改善:PTA前平均ABI为0.69(SD 0.19),PTA后为1.06(SD 0.15)。

结论

内膜切除术是治疗限于腹主动脉远端闭塞性疾病的安全有效方法。PTA似乎不太可靠。然而,对于血管造影显示病变合适的患者,推荐将其作为初始治疗选择,因为其侵入性较小。

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