Ishihama Y, Oda Y, Uchikawa K, Asakawa N
Department of Physical and Analytical Chemistry, Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki, Japan.
Chem Pharm Bull (Tokyo). 1994 Jul;42(7):1525-7. doi: 10.1248/cpb.42.1525.
Micellar electrokinetic chromatography (MEKC) was used to measure hydrophobicity of 18 aromatic compounds. The capacity factors, which are proportional to the micelle-water distribution coefficients, were closely correlated with the octanol-water partition coefficients. The addition of Brij 35 to the charged micelle was effective in improving the correlation because the surface charges of the micelle were shielded.
