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发展中国家的药品质量筛查:在斯威士兰建立合适的实验室。

Drug quality screening in developing countries: establishment of an appropriate laboratory in Swaziland.

作者信息

Kenyon T A, Kenyon A S, Sibiya T

机构信息

Project HOPE, Millwood, VA.

出版信息

Bull World Health Organ. 1994;72(4):615-20.

PMID:7923541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2486607/
Abstract

A simple, low-cost, accurate thin-layer chromatography (TLC) method has been used to establish the first drug quality screening laboratory in Swaziland. For this purpose, office space at the central medical stores was first converted into a simple laboratory. Basic equipment, supplies, and materials were purchased, existing manpower was trained to perform accurately the TLC procedure, and a system was established for the qualitative/quantitative screening of selected drugs purchased by the Ministry of Health prior to their distribution to user facilities. The TLC method described can be used to set up similar low-cost, drug quality screening laboratories in other developing countries where analytical chemistry expertise is lacking, resources are scarce, and sophisticated analytical laboratories to assess drug quality are not available.

摘要

一种简单、低成本且准确的薄层色谱法(TLC)已被用于在斯威士兰建立首个药品质量筛查实验室。为此,中央医疗用品仓库的办公空间首先被改造成一个简易实验室。购置了基本设备、用品和材料,对现有人员进行培训使其能准确执行TLC程序,并建立了一个系统,用于对卫生部采购的选定药品在分发至使用机构之前进行定性/定量筛查。所描述的TLC方法可用于在其他缺乏分析化学专业知识、资源稀缺且没有先进分析实验室来评估药品质量的发展中国家建立类似的低成本药品质量筛查实验室。

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本文引用的文献

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A simple, inexpensive thin-layer chromatography method for the analysis of theophylline tablets.一种用于分析茶碱片的简单、廉价的薄层色谱法。
Bull World Health Organ. 1989;67(5):555-9.
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Combating counterfeit drugs.打击假药
Nature. 1992 Jan 16;355(6357):192. doi: 10.1038/355192a0.