Parkman H P, Ogorek C P, Harris A D, Cohen S
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Dig Dis Sci. 1994 Oct;39(10):2102-8. doi: 10.1007/BF02090357.
The optimal management of reflux-induced esophageal strictures that occur after esophagomytomy for achalasia is uncertain. This paper presents our experience with the nonsurgical treatment of postesophagomyotomy strictures in achalasia patients using endoscopic dilation and gastric acid suppression. Six patients with achalasia who had undergone prior esophagomyotomy subsequently developed recurrent dysphagia and were found to have an esophageal stricture. Esophagrams typically showed a markedly dilated esophagus with a narrowed, sharply angulated gastroesophageal junction. Esophageal manometry confirmed esophageal aperistalsis and, when measured, the LES pressure was < 5 mm Hg. Endoscopy showed esophageal inflammation and a fixed stricture at the gastroesophageal junction. Strictures were dilated under direct visualization using through-the-scope balloon dilators. Patients began gastric acid suppressive treatment at the same time. Five patients who remained symptomatic underwent repeat endoscopy, which demonstrated improvement in esophagitis. Dilation was then repeated with a larger balloon dilator. Over a mean follow-up period of 3.8 years, the average number of repeat dilations per patient was 3.6 (range: 0-12). All patients had symptomatic improvement and weight gain. No patient required surgery. We conclude that esophageal strictures after esophagomyotomy for achalasia can be safely treated using endoscopic dilation and gastric acid suppression, thus avoiding the need for reoperation.
贲门失弛缓症行食管肌层切开术后发生的反流性食管狭窄的最佳治疗方法尚不确定。本文介绍了我们使用内镜扩张和抑制胃酸对贲门失弛缓症患者食管肌层切开术后狭窄进行非手术治疗的经验。6例曾接受食管肌层切开术的贲门失弛缓症患者随后出现复发性吞咽困难,经检查发现有食管狭窄。食管造影通常显示食管明显扩张,胃食管交界处狭窄且呈锐角。食管测压证实食管无蠕动,测量时LES压力<5mmHg。内镜检查显示食管炎症及胃食管交界处有固定狭窄。在直视下使用经内镜球囊扩张器对狭窄进行扩张。患者同时开始进行胃酸抑制治疗。5例仍有症状的患者接受了重复内镜检查,结果显示食管炎有所改善。然后使用更大的球囊扩张器再次进行扩张。在平均3.8年的随访期内,每位患者重复扩张的平均次数为3.6次(范围:0 - 12次)。所有患者症状均有改善且体重增加。无患者需要手术治疗。我们得出结论,贲门失弛缓症行食管肌层切开术后的食管狭窄可通过内镜扩张和抑制胃酸安全治疗,从而避免再次手术的需要。