在接受冠状动脉旁路移植术（CABG）手术的患者中，罗库溴铵与维库溴铵血流动力学效应的比较。
Comparison of haemodynamic effects of rocuronium bromide with those of vecuronium in patients undergoing CABG surgery.
作者信息
Nitschmann P, Oberkogler W, Hertsig M, Schwarz S
机构信息
Clinical Services Group, Organon Teknika NV, Turnhout, Belgium.
出版信息
Eur J Anaesthesiol Suppl. 1994;9:113-5.
In a double-blind study, cardiovascular parameters (cardiac output, heart rate, systolic and diastolic arterial pressure, pulmonary and systemic vascular resistances) were measured invasively in two groups of patients receiving 3 x ED90 of rocuronium or vecuronium. Measurements were made at 2, 5 and 7 min after administration and 10 and 15 min after subsequent intubation. Systemic vascular resistance mostly increased, sometimes quite markedly, although, because of the variability, rarely statistically significantly. However, heart rate, arterial pressure and cardiac output were not altered to a clinically relevant degree.
在一项双盲研究中，对两组接受3倍罗库溴铵或维库溴铵ED90剂量的患者进行有创测量心血管参数（心输出量、心率、动脉收缩压和舒张压、肺血管阻力和体循环血管阻力）。在给药后2分钟、5分钟和7分钟以及随后插管后10分钟和15分钟进行测量。体循环血管阻力大多增加，有时相当明显，不过，由于存在变异性，很少有统计学上的显著差异。然而，心率、动脉血压和心输出量并未发生具有临床意义的改变。
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