Shvero J, Hadar T, Segal K, Yaniv E, Marshak G, Feinmesser R
Department of Otolaryngology, Beilinson Medical Center, Petah Tiqva, Israel.
Eur J Surg Oncol. 1994 Oct;20(5):557-60.
This study reviews the records of 56 patients with early glottic carcinoma involving the anterior commissure (T1N0M0) who were treated between 1958 and 1988 at Beilinson Medical Center. Five- and 10-year survival rates were 82% and 60%, respectively. Most failures were local (15 patients). In addition, three patients who were treatment failures had neck lesions (regional failure) and one had lung lesions (distant metastases). All 56 patients received irradiation as the only mode of initial treatment. The effectiveness of irradiation for anterior commissure lesions is therefore evaluated. The study supports previous reports suggesting that glottic carcinoma involving the anterior commissure is associated with a high rate of treatment failure.
本研究回顾了1958年至1988年期间在贝林森医疗中心接受治疗的56例累及前联合的早期声门癌（T1N0M0）患者的记录。5年和10年生存率分别为82%和60%。大多数治疗失败为局部复发（15例患者）。此外，3例治疗失败患者出现颈部病变（区域复发），1例出现肺部病变（远处转移）。所有56例患者均接受放疗作为初始治疗的唯一方式。因此，对放疗治疗前联合病变的有效性进行了评估。该研究支持了之前的报告，即累及前联合的声门癌与高治疗失败率相关。
