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与早产儿脑损伤相关的视力损害模式。

Patterns of visual impairment associated with lesions of the preterm infant brain.

作者信息

Pike M G, Holmstrom G, de Vries L S, Pennock J M, Drew K J, Sonksen P M, Dubowitz L M

机构信息

Hospital for Sick Children, Headington, Oxford, UK.

出版信息

Dev Med Child Neurol. 1994 Oct;36(10):849-62. doi: 10.1111/j.1469-8749.1994.tb11776.x.

DOI:10.1111/j.1469-8749.1994.tb11776.x
PMID:7926317
Abstract

The visual function of 42 children with haemorrhagic and/or ischaemic cerebral lesions acquired before a gestational age of 35 weeks was examined and related to cranial ultrasound in the neonatal period and to MRI and neurodevelopmental status at follow-up. All 37 children with abnormal ultrasound scans and one of the five with normal ultrasound scans showed impairment of one or more aspects of visual function. While impaired acuity was more frequent among infants with MRI evidence of visual pathway damage, this was not an invariable finding. Normal or near-normal visual acuity did not preclude the presence of other functional visual deficits. The authors conclude that preterm cerebral insults may produce a variety of visual difficulties, the pattern and severity of which cannot be predicted on imaging. Each child therefore requires individual assessment of multiple aspects of visual function.

摘要

对42名在孕35周前发生出血性和/或缺血性脑损伤的儿童的视觉功能进行了检查,并将其与新生儿期的头颅超声以及随访时的MRI和神经发育状况相关联。37名超声扫描异常的儿童和5名超声扫描正常的儿童中的1名,均表现出视觉功能一个或多个方面的损害。虽然在有MRI证据显示视觉通路受损的婴儿中,视力受损更为常见,但这并非一成不变的发现。正常或接近正常的视力并不能排除其他功能性视觉缺陷的存在。作者得出结论,早产脑损伤可能会导致多种视觉困难,其模式和严重程度无法通过影像学预测。因此,每个儿童都需要对视觉功能的多个方面进行个体评估。

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