Randall G M, Jensen D M, Machicado G A, Hirabayashi K, Jensen M E, You S, Pelayo E
West Los Angeles Veterans Administration, University of California.
Gastrointest Endosc. 1994 Jul-Aug;40(4):403-10. doi: 10.1016/s0016-5107(94)70201-2.
Internal hemorrhoids are the most common cause of lower gastrointestinal bleeding. Although new anoscopic therapies are available, few comparative randomized studies have evaluated them in regard to long-term efficacy, recurrence rates, and safety. Our purpose was to compare the treatment of internal hemorrhoids with direct current (Ultroid, Cabot Medical, Langhorn, Pa.) and bipolar (BICAP, Circon ACMI, Stamford, Conn.) hemorrhoid probes. One hundred patients with symptomatic internal hemorrhoids were randomized: 50 to direct current electrocoagulation and 50 to bipolar electrocoagulation. Follow-up and treatment were at 3- to 4-weekly intervals; two to three hemorrhoid segments were treated at each session until relief of symptoms (bleeding, prolapse, and discharge) and a reduction in hemorrhoid size to grade 1 or 0 were noted. The hemorrhoids of 98% of all patients studied were grade 2 or 3; 2% of patients had grade 1 hemorrhoids and none had grade 4 hemorrhoids. At 1 year after treatment, most patients had no (69%) or only mild (23%) recurrence, and a few had severe, symptomatic (8%) hemorrhoid recurrence. A greater recurrence rate was noted after direct current treatment (34%) than bipolar treatment (29%). In contrast, rebleeding at 1 year occurred less frequently after direct current treatment (5%) than after bipolar treatment (20%). Our conclusions were as follows: (1) Both direct current and bipolar probes were effective for control of chronic bleeding from grade 1 to 3 internal hemorrhoids. (2) Bipolar probe was significantly faster than direct current probe. (3) Direct current treatment produced fewer complications than bipolar treatment (12% versus 14%). (4) Recurrence rates were low after 1 year with either device (8%).(ABSTRACT TRUNCATED AT 250 WORDS)
内痔是下消化道出血最常见的原因。尽管有新的肛门镜治疗方法,但很少有比较随机研究评估它们在长期疗效、复发率和安全性方面的情况。我们的目的是比较直流电(Ultroid,卡博特医疗公司,宾夕法尼亚州兰霍恩)和双极(BICAP,Circon ACMI公司,康涅狄格州斯坦福德)痔疮探头治疗内痔的效果。100例有症状的内痔患者被随机分组:50例接受直流电电凝治疗,50例接受双极电凝治疗。随访和治疗每隔3至4周进行一次;每次治疗两到三个痔段,直到症状(出血、脱垂和分泌物)缓解且痔大小缩小至1级或0级。所有研究患者中98%的痔为2级或3级;2%的患者为1级痔,无4级痔患者。治疗后1年,大多数患者无复发(69%)或仅有轻度复发(23%),少数患者有严重的、有症状的痔复发(8%)。直流电治疗后的复发率(34%)高于双极治疗(29%)。相比之下,直流电治疗后1年再次出血的发生率(5%)低于双极治疗(20%)。我们的结论如下:(1)直流电和双极探头对控制1至3级内痔的慢性出血均有效。(2)双极探头比直流电探头显著更快。(3)直流电治疗产生的并发症比双极治疗少(12%对14%)。(4)使用任何一种设备治疗1年后复发率都较低(8%)。(摘要截断于250字)