Geppert M, Smyczek-Gargya B, Blum S, Schrage R, Menton M
Universitäts-Frauenklinik Tübingen.
Geburtshilfe Frauenheilkd. 1994 Jul;54(7):394-6. doi: 10.1055/s-2007-1022864.
133 patients attending the colposcopy-laser outpatient consultations were examined simultaneously by cytology, colposcopy and punch biopsy. A cone biopsy was taken 25 patients and one patient was hysterectomised later. A comparison between cytology and histology revealed 17.1% false negative smear results. Cytology and histology showed the same result in 84.6%. The highest percentage of high-grade dysplasia was found in colposcopy with signs of punctation and/or mosaicism. A similar diagnosis was achieved in 92.3% of cases comparing punch with cone biopsy. Simultaneous use of cytology, colposcopy and punch biopsy enables reliable diagnosis and follow-up of dysplastic lesions of the cervix. Besides, one can use punch biopsy as basic histology for local destructive manoeuvres such as laser vaporisation.
133名前来接受阴道镜-激光门诊会诊的患者同时接受了细胞学、阴道镜和穿刺活检检查。25名患者进行了锥形活检,1名患者后来接受了子宫切除术。细胞学与组织学的比较显示,涂片结果假阴性率为17.1%。细胞学和组织学结果在84.6%的病例中相同。在有 punctation 和/或镶嵌征迹象的阴道镜检查中发现高级别发育异常的比例最高。在92.3%的病例中,穿刺活检与锥形活检的诊断结果相似。同时使用细胞学、阴道镜和穿刺活检能够可靠地诊断和随访宫颈发育异常病变。此外,穿刺活检可作为局部破坏性操作(如激光汽化)的基础组织学检查。