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一个中央凹视锥细胞对应多少神经节细胞?对一名正常人中央凹视锥细胞与神经节细胞数量关系的体视学分析。

How many ganglion cells are there to a foveal cone? A stereologic analysis of the quantitative relationship between cone and ganglion cells in one normal human fovea.

作者信息

Sjöstrand J, Conradi N, Klarén L

机构信息

Department of Ophthalmology, University of Göteborg, Sahlgren's Hospital, Sweden.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1994 Jul;232(7):432-7. doi: 10.1007/BF00186586.

DOI:10.1007/BF00186586
PMID:7926876
Abstract

Published studies on humans and monkeys show discrepancies in the reported quantitative relationship between cones (C) and ganglion cells (G). Data on human foveal retina suggest that it cannot accommodate the midget on-off system in addition to other functional channels. Foveal cell densities along the vertical meridian (0-1.8 mm eccentricity) were estimated in one normal human retina using the disector method. Cell ratios were calculated from cumulative total numbers. G density peaked at 0.65 mm eccentricity and C density at the foveola. Cumulative cell numbers showed a more rapid increase in G than in C with increasing eccentricity. G/C ratios of 2.7-3.4 were found using lateral displacement data modified from macaque. Using one estimate of displacement from the sections, the G/C ratio was 3.0. This study shows that there are on average three ganglion cells per foveal cone in humans, as in monkeys.

摘要

关于人类和猴子的已发表研究表明,在报道的视锥细胞(C)和神经节细胞(G)之间的定量关系上存在差异。关于人类中央凹视网膜的数据表明,除了其他功能通道外,它无法容纳侏儒型开-关系统。使用分割法在一只正常人的视网膜中估计了沿垂直子午线(偏心度0-1.8毫米)的中央凹细胞密度。根据累积总数计算细胞比率。G密度在偏心度0.65毫米处达到峰值,C密度在中央小凹处达到峰值。随着偏心度增加,累积细胞数量显示G比C增加得更快。使用从猕猴修改而来的横向位移数据,发现G/C比率为2.7-3.4。根据切片的一种位移估计,G/C比率为3.0。这项研究表明,与猴子一样,人类中央凹视锥细胞平均每个有三个神经节细胞。

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