Cohen O, River Y, Zelinger I
Dept. of Neurology, Hadassah-University Hospital, Jerusalem.
Harefuah. 1994 Jun 15;126(12):707-10, 763.
Several recent reports have described convulsions in patients with celiac disease, and in some, folic acid deficiency and brain calcifications. A 40-year-old woman with celiac disease, hypocalcemia and generalized tonic-clonic seizures is reported. Hypocalcemia was corrected and convulsions disappeared, but the EEG showed persistent occipital epileptiform activity. Patients with celiac disease and hypocalcemia due to malabsorption are particularly at increased risk for convulsions. Therefore, even a mild degree of hypocalcemia in these patients should be corrected as soon as possible.
最近有几份报告描述了乳糜泻患者的惊厥情况,其中一些患者还伴有叶酸缺乏和脑钙化。本文报告了一名40岁患有乳糜泻、低钙血症并伴有全身强直阵挛性发作的女性患者。低钙血症得到纠正后惊厥消失,但脑电图显示枕叶持续存在癫痫样活动。患有乳糜泻且因吸收不良导致低钙血症的患者惊厥风险尤其增加。因此,这些患者即使是轻度低钙血症也应尽快纠正。