Funck R, Herzum M, Barth P J, Bethge C, Maisch B
Abteilung Innere Medizin-Kardiologie, Philipps-Universität Marburg.
Herz. 1994 Jun;19(3):149-51.
The case of a 76-year-old diabetic patient with known aortic valve sclerosis is reported. One week after implantation of a permanent pacemaker system (indication: 2nd degree AV-block type Mobitz) he developed fever. Large endocarditic vegetations were found on the aortic and mitral valve (blood cultures: were positive for Staphylococcus aureus). Also from the pacemaker bed Staphylococcus aureus was isolated and an antibiotic treatment including vancomycin was started. Nevertheless the patient developed insufficiencies of both the aortic and mitral valves and became hemodynamically unstable. Due to cerebral embolisms and further deterioration of the patient's overall clinical state the already planned operative replacement of the aortic and mitral valve could not be performed. The patient died because of left ventricular failure after pacemaker infection which was complicated by endocarditis.
报告了一例76岁已知患有主动脉瓣硬化的糖尿病患者的病例。在植入永久性起搏器系统(指征:莫氏Ⅱ度房室传导阻滞)一周后,他出现发热。在主动脉瓣和二尖瓣上发现了大的感染性赘生物(血培养:金黄色葡萄球菌阳性)。从起搏器植入部位也分离出了金黄色葡萄球菌,并开始了包括万古霉素在内的抗生素治疗。然而,患者出现了主动脉瓣和二尖瓣关闭不全,血流动力学变得不稳定。由于脑栓塞以及患者整体临床状态的进一步恶化,原计划的主动脉瓣和二尖瓣手术置换无法进行。患者因起搏器感染并发心内膜炎后出现左心室衰竭而死亡。