Raivich G, Kreutzberg G W
Department of Neuromorphology, Max-Planck Institute for Psychiatry, Martinsried, Germany.
Glia. 1994 Jun;11(2):129-46. doi: 10.1002/glia.440110208.
Activation and proliferation of glial cells are common events in the pathology of the nervous system. Although we are only beginning to understand the molecular signals leading to glial activation in vivo, there is increasing evidence that growth factors and their receptors may play an important part. In this paper we summarize the data on the pathophysiology of glial growth factor receptors and their ligands in the central and peripheral nervous systems.
神经胶质细胞的激活和增殖是神经系统病理学中的常见现象。尽管我们才刚刚开始了解体内导致神经胶质细胞激活的分子信号，但越来越多的证据表明生长因子及其受体可能起着重要作用。在本文中，我们总结了关于中枢和外周神经系统中神经胶质生长因子受体及其配体病理生理学的数据。
