Rinieris P M, Christodoulou G N, Souvatzoglou A M, Koutras D A, Stefanis C N
Acta Psychiatr Belg. 1978 Mar-Apr;78(2):248-55.
The thyroid function of 20 female inpatients with primary depression was investigated by the following tests: serum thyroxine, in vitro radioactive triiodothyronine uptake, free-thyroxine index, thyroidal 131I uptake and 48 hours protein-bound 131I. The mean values of serum thyroxine, free-thyroxine index and thyroidal 131I uptake of the patients were found decreased, compared to those of the euthyroid controls (to a statistically significant level for serum thyroxine and free-thyroxine index P less than .001). These findings point to a decreased thyroid activity in primary depression. The possibility of implication of a common neurochemical mechanism in both primary depression and thyroid hypoactivity was discussed.
通过以下检测对20名原发性抑郁症女性住院患者的甲状腺功能进行了研究：血清甲状腺素、体外放射性三碘甲状腺原氨酸摄取、游离甲状腺素指数、甲状腺131I摄取及48小时蛋白结合131I。与甲状腺功能正常的对照组相比，患者的血清甲状腺素、游离甲状腺素指数及甲状腺131I摄取的平均值均降低（血清甲状腺素和游离甲状腺素指数P小于.001，具有统计学意义）。这些发现表明原发性抑郁症患者甲状腺活性降低。本文还讨论了原发性抑郁症和甲状腺功能减退可能存在共同神经化学机制的可能性。
