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头颈部鳞状细胞癌的放射免疫闪烁显像

Radioimmunoscintigraphy of squamous cell carcinoma in the head and neck region.

作者信息

Heissler E, Grünert B, Barzen G, Fritsche L, Hell B, Felix R, Bier J

机构信息

Clinic for Maxillofacial Surgery, University Clinic Rudolf Virchow, Free University of Berlin, Germany.

出版信息

Int J Oral Maxillofac Surg. 1994 Jun;23(3):149-52. doi: 10.1016/s0901-5027(05)80289-9.

DOI:10.1016/s0901-5027(05)80289-9
PMID:7930767
Abstract

Radioimmunoscintigraphy (RIS) with a monoclonal antibody (SQ 174, Biomira, Inc, Canada) is introduced as a new diagnostic method for detection of squamous cell carcinoma in the head and neck region. RIS could detect eight of the 10 primary tumors. One patient had histopathologically proven nodal disease. This lymph node was seen in RIS. No false positive results were seen in RIS, whereas sonography, computed tomography, and magnetic resonance imaging showed several false positive results.

摘要

采用单克隆抗体(SQ 174,加拿大Biomira公司)的放射免疫闪烁显像(RIS)被引入作为检测头颈部鳞状细胞癌的一种新的诊断方法。RIS能够检测出10例原发性肿瘤中的8例。1例患者经组织病理学证实有淋巴结病变。该淋巴结在RIS中显影。RIS未出现假阳性结果,而超声、计算机断层扫描和磁共振成像显示有几个假阳性结果。

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