8-羟基青霉酸：核磁共振特征及由6-氨基青霉烷酸的简便合成
8-Hydroxypenillic acid: NMR characteristics and facile formation from 6-aminopenicillanic acid.
作者信息
Casy A F, Lipczynski A
机构信息
School of Pharmacy and Pharmacology, University of Bath, UK.
出版信息
J Pharm Pharmacol. 1994 Jun;46(6):533-4. doi: 10.1111/j.2042-7158.1994.tb03848.x.
Abstract
High field NMR (1H and 13C) spectral characteristics in D2O of 8-hydroxypenillic acid and 6-aminopenicillanic acid (6-APA)-sodium bicarbonate mixtures are reported. The ready conversion of 6-APA to 8-hydroxypenillic acid is demonstrated.
摘要
报道了8-羟基青霉烯酸与6-氨基青霉烷酸（6-APA）-碳酸氢钠混合物在重水中的高场核磁共振（1H和13C）光谱特征。证实了6-APA可轻易转化为8-羟基青霉烯酸。
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