人源单克隆IgM类风湿因子（2A2）Fab片段的结晶及初步X射线分析
Crystallization and preliminary X-ray analysis of the Fab fragment of a human monoclonal IgM rheumatoid factor (2A2).
作者信息
Sohi M K, Sutton B J, Corper A L, Wan T, Maini R N, Brown C, Rijnders T, Beale D, Feinstein A, Humphreys A S
机构信息
Randall Institute, King's College London, U.K.
出版信息
J Mol Biol. 1994 Oct 7;242(5):706-8. doi: 10.1006/jmbi.1994.1620.
Crystals of the Fab fragment of a human monoclonal IgM rheumatoid factor have been obtained and are suitable for X-ray structure determination. This molecule, derived from the synovial B cells of a patient with rheumatoid arthritis, is an autoantibody with specificity for IgG Fc. The crystals have space group P2(1), cell dimensions a = 69.0 A, b = 76.6 A, c = 98.8 A and beta = 90.6 degrees, and diffract to a resolution of at least 2.8 A.
已获得人单克隆IgM类风湿因子Fab片段的晶体，适用于X射线结构测定。该分子源自一名类风湿性关节炎患者的滑膜B细胞，是一种对IgG Fc具有特异性的自身抗体。晶体的空间群为P2(1)，晶胞参数a = 69.0 Å，b = 76.6 Å，c = 98.8 Å，β = 90.6°，衍射分辨率至少为2.8 Å。
Zotero 插件