Fukuda T, Naito H
Department of Anesthesia, Oyama Municipal Hospital.
Masui. 1994 Jul;43(7):993-7.
We examined the effects of epinephrine and sodium bicarbonate in the hemodynamics after epidural anesthesia. The solution was prepared by adding 2 ml of either 7% sodium bicarbonate or saline to 1% lidocaine 20 ml with or without epinephrine (1:200,000) and we gave 3 ml of each solution in the epidural space of dogs anesthetized with halothane. Epinephrine and sodium bicarbonate addition exerted no significant influence on the hemodynamics except tendency to continuous hypotension. Although sodium bicarbonate addition tended to decrease heart rate, the decrease was not significant and the duration of hypotension was short.
我们研究了肾上腺素和碳酸氢钠对硬膜外麻醉后血流动力学的影响。通过向20毫升1%利多卡因中加入2毫升7%碳酸氢钠或生理盐水，制备成含或不含肾上腺素（1:200,000）的溶液，然后将每种溶液3毫升注入用氟烷麻醉的犬的硬膜外腔。除了有持续低血压的趋势外，添加肾上腺素和碳酸氢钠对血流动力学没有显著影响。虽然添加碳酸氢钠有使心率下降的趋势，但下降不显著，且低血压持续时间较短。
