Kubota T, Küchle M, Nguyen N X
Department of Ophthalmology, University Erlangen-Nürnberg, Germany.
Jpn J Ophthalmol. 1994;38(1):67-70.
It is unknown whether aqueous flare is increased in eyes with prominent fundus lesions other than choroidal malignant melanoma. Therefore, we studied the aqueous flare in eyes with age-related macular degeneration (ARMD) using the laser flare-cell meter. Forty-three eyes of 27 patients with ARMD (age 67.0 +/- 14.0 years, range 43-81 years), and 41 healthy eyes of 41 randomly selected age- and gender-matched control patients (age 68.9 +/- 9.8 years, range 43-89 years) were examined. The macular degeneration was diagnosed and classified using fluorescein angiograms. Flare values in eyes with ARMD were 0.28 +/- 0.18 mg/ml, being significant in comparison with the control (0.12 +/- 0.05 mg/ml). The differences among the subgroups of ARMD were not statistically significant (P > 0.5): macular drusenosis (0.21 +/- 0.05 mg/ml, n = 6), subretinal neovascularization without marked subretinal hemorrhage (0.27 +/- 0.15 mg/ml, n = 19), subretinal neovascularization with marked subretinal hemorrhage (0.29 +/- 0.24 mg/ml, n = 7), and disciform scar (0.31 +/- 0.24 mg/ml, n = 9).
除脉络膜恶性黑色素瘤外，眼底病变显著的眼中房水闪光是否增加尚不清楚。因此，我们使用激光闪光细胞仪研究了年龄相关性黄斑变性（ARMD）患者眼睛的房水闪光情况。对27例ARMD患者的43只眼睛（年龄67.0±14.0岁，范围43 - 81岁）以及41例随机选取的年龄和性别匹配的对照患者的41只健康眼睛（年龄68.9±9.8岁，范围43 - 89岁）进行了检查。使用荧光素血管造影对黄斑变性进行诊断和分类。ARMD患者眼睛的闪光值为0.28±0.18mg/ml，与对照组（0.12±0.05mg/ml）相比有显著差异。ARMD各亚组之间的差异无统计学意义（P>0.5）：黄斑玻璃膜疣（0.21±0.05mg/ml，n = 6）、无明显视网膜下出血的视网膜下新生血管形成（0.27±0.15mg/ml，n = 19）、有明显视网膜下出血的视网膜下新生血管形成（0.29±0.24mg/ml，n = 7）和盘状瘢痕（0.31±0.24mg/ml，n = 9）。
