[持续性贾第虫病患者中HLA抗原分布特征]
[The characteristics of HLA antigen distribution among patients with persistent lambliasis].
作者信息
Osipova S O, Niiazova O P, Shimolin A P, Dekhkan-Khodzhaeva N A
出版信息
Med Parazitol (Mosk). 1994 Apr-Jun(2):11-3.
PMID:7935180
Abstract
Fifty patients suffering from persistent giardiasis and 257 healthy persons from Uzbekistan were examined. HLA-typing was carried out by the Terasaki microlymphocytotoxicity technique. The patients with persistent giardiasis were characterized as a significant prevalence of HLA-B5, HLA-B14, HLA-DR3, DR4, DR7 and haplotypes HLA-A9-B5 and A1-B5. These haplotypes and HLA antigens can be considered as markers of predisposition to persistent giardiasis.
摘要
对来自乌兹别克斯坦的50名持续性贾第虫病患者和257名健康人进行了检查。采用Terasaki微量淋巴细胞毒性技术进行HLA分型。持续性贾第虫病患者的特征是HLA - B5、HLA - B14、HLA - DR3、DR4、DR7以及单倍型HLA - A9 - B5和A1 - B5显著流行。这些单倍型和HLA抗原可被视为持续性贾第虫病易感性的标志物。
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