印度南部泰米尔纳德邦德拉威族印度教徒中HLA（I类和II类）抗原的分布情况。
Distribution of HLA (class I and class II) antigens in the native Dravidian Hindus of Tamil Nadu, south India.
作者信息
Subramanian V S, Selvaraj P, Narayanan P R, Prabhakar R, Damodaran C
机构信息
Tuberculosis Research Centre (ICMR), Madras, India.
出版信息
Gene Geogr. 1995 Apr;9(1):15-24.
HLA - A, B, C, DR, DQ antigen profile of South Indian Tamil-speaking Hindus of Dravidian descent was studied. Phenotype, gene and haplotype frequencies were calculated and compared with the literature. There was a complete lack of A23, A25 and A32 antigens in the sample presently monitored. Except for minor differences (higher incidence of Cw6 and DR10 antigens), the Dravidian Hindus show similarity to North Indio-Aryan and other Hindu samples. The haplotypes A1, B17; A2, B5; A2, B51; A1, DR7; B12, DR7; B13, DR2; B17, DR7; DR2, DQ1; DR3, DQ2; DR4, DQ3; DR5, DQ3; DR7, DQ2; DR11, DQ3; show significant positive linkage disequilibrium whereas A1, DR2; DR2, DQ2; DR7, DQ1 were significant for negative linkage disequilibrium in the Dravidian Hindus.
对南印度讲泰米尔语的达罗毗荼族印度教徒的HLA - A、B、C、DR、DQ抗原谱进行了研究。计算了表型、基因和单倍型频率，并与文献进行了比较。在目前监测的样本中完全缺乏A23、A25和A32抗原。除了微小差异（Cw6和DR10抗原发生率较高）外，达罗毗荼族印度教徒与北印度 - 雅利安人和其他印度教样本相似。单倍型A1、B17；A2、B5；A2、B51；A1、DR7；B12、DR7；B13、DR2；B17、DR7；DR2、DQ1；DR3、DQ2；DR4、DQ3；DR5、DQ3；DR7、DQ2；DR11、DQ3显示出显著的正连锁不平衡，而A1、DR2；DR2、DQ2；DR7、DQ1在达罗毗荼族印度教徒中显示出显著的负连锁不平衡。
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