Vescovi P, Zucchi A, Bonanini M, Pizzi S, Gennari P U
Istituto di Clinica Odontoiatrica, Università degli Studi, Parma.
Minerva Stomatol. 1994 Jun;43(6):301-7.
Erythema multiforme (EM) is characterised by a polymorphous eruptive complex which many involve the cutis and oral, genital and conjunctival mucous. Its etiopathogenesis is unclear: it is thought to be associated with various viral or bacterial infective agents (herpes virus, Coxsackie virus, mycoplasmas, etc.), numerous drugs, physical therapy, systemic pathologies of various types. The authors report their experience in relation to 11 patients suffering from EM; the clinical characteristics of each case are reported, together with the course of disease, and the diagnostic and therapeutic protocol adopted. The discussion examines the possible cause of disease: in 5 patients the etiology was traced back to viral infections (4 herpes and 1 coxsackie) and to the administration of drugs in the remaining cases (4 in relation to anti-phlogistic agents and 2 regarding antibiotics).
多形红斑（EM）的特征是多形性发疹复合体，可累及皮肤以及口腔、生殖器和结膜黏膜。其发病机制尚不清楚：据认为与多种病毒或细菌感染因子（疱疹病毒、柯萨奇病毒、支原体等）、多种药物、物理治疗以及各种类型的全身性疾病有关。作者报告了他们对11例多形红斑患者的治疗经验；报告了每个病例的临床特征、疾病进程以及所采用的诊断和治疗方案。讨论探讨了可能的病因：5例患者的病因可追溯到病毒感染（4例为疱疹病毒感染，1例为柯萨奇病毒感染），其余病例的病因与药物使用有关（4例与抗炎药有关，2例与抗生素有关）。
