Hunáková L, Duraj J, Holománová D, Sedlák J, Chorváth B
Cancer Research Institute, Slovak Academy of Sciences, Bratislava.
Neoplasma. 1994;41(3):129-35.
Flow cytometric and immunochemical studies performed with the CD66/67 panel antibodies from the Vth International Workshop on Leukocyte Antigens allowed to subdivide these antibodies into five groups, according to the molecular weights of polypeptides recognized by these antibodies on pooled healthy donor granulocytes. Although some monoclonal antibodies recognized either 95-110 kDa, or 160-180 kDa polypeptides, majority of the examined antibodies reacted with epitopes shared by both 95-110 kDa and 160-180 kDa polypeptides. Differential TPA-induced modulation of recognized antigens was observed with HL-60 and U-937 leukemia/lymphoma cell lines.
使用来自第五届白细胞抗原国际研讨会的CD66/67组抗体进行的流式细胞术和免疫化学研究，根据这些抗体在汇集的健康供体粒细胞上识别的多肽分子量，可将这些抗体分为五组。尽管一些单克隆抗体识别95 - 110 kDa或160 - 180 kDa的多肽，但大多数检测的抗体与95 - 110 kDa和160 - 180 kDa多肽共有的表位发生反应。在HL - 60和U - 937白血病/淋巴瘤细胞系中观察到佛波酯（TPA）诱导的识别抗原的差异调节。
