Guthikonda M, Rengachary S S, Balko M G, van Loveren H
Department of Neurosurgery, Wayne State University, Detroit, Michigan.
Neurosurgery. 1994 Jul;35(1):127-32. doi: 10.1227/00006123-199407000-00019.
The authors report a case of lipofibromatous hamartoma of the median nerve in a patient who presented with symptoms of carpal tunnel syndrome. The diagnosis was made by magnetic resonance imaging and confirmed by intraoperative findings and histological diagnosis; distinctive magnetic resonance imaging features of this entity are described. In this patient, surgery was limited to biopsy to confirm the diagnosis and external neural decompression, which helped to stop the progression of the symptoms. In their review of the literature, the authors found four types of lipomatous masses in the extremities affecting the function of peripheral nerves, commonly the median nerve. Treatment and the extent of surgery differ for each patient, based on the anatomical findings and extent of neurological deficit. The etiology, pathogenesis, differential diagnosis, and surgical management of lipofibromatous hamartoma are described.
作者报告了一例正中神经脂肪纤维瘤性错构瘤患者，该患者表现为腕管综合征症状。诊断通过磁共振成像做出，并经术中发现及组织学诊断证实；文中描述了该病变独特的磁共振成像特征。在该患者中，手术仅限于活检以确诊及进行外部神经减压，这有助于阻止症状进展。作者在文献回顾中发现，四肢有四种脂肪瘤样肿物会影响周围神经功能，通常是正中神经。根据解剖学发现及神经功能缺损程度，每位患者的治疗方法及手术范围有所不同。本文描述了脂肪纤维瘤性错构瘤的病因、发病机制、鉴别诊断及手术治疗。
