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[共识会议。节约用血:仍存在哪些疑问和问题?]

[Consensus conference. Saving blood: which are still the doubts and the problems?].

作者信息

Caroli G C, Borghi B, Pappalardo G, Oriani G, Valbonesi M, Ferrari M, Zanoni A, Miletto A, Mercuriali F, Conconi F

机构信息

I Servizio di Anestesia e Rianimazione, IRCCS Istituti Ortopedici Rizzoli di Bologna.

出版信息

Minerva Anestesiol. 1994 May;60(5):285-93.

PMID:7936346
Abstract

The consensus conference on blood saving has allowed us to formulate some interesting guidelines. The autologous and homologous transfusion require the patient's consent. For volemic replacement crystalloid solutions are used for phlebotomies below 10-15%, and colloid solutions for those greater than 10-15% of the blood mass. Severe isovolemic hemodilution (Ht < 20%) necessitates the reduction of the dosage of some drugs. A limit of Hb around 9 g/dl after phlebotomy may be acceptable in the absence of cerebral and coronary vascular disease. Phlebotomies are therefore possible also when the Hb values are 10 g/dl (Ht 30%). Hb values around 7 g/dl in the late postoperative period (from day 3 to 6) may be accepted only if well tolerated. The blood salvaged during surgery and at the beginning of the postoperative phase must always be centrifugated, washed and microfiltered. Subsequently, in the first 8 hours it is possible to reinfuse red cells after sedimentation and microfiltration. The techniques of predeposit, hemodilution and recovery are valid especially if associated with careful control of postoperative bleeding by means of aspiration under controlled pressure (at minimum negative values and sometimes positive ones), monitoring of blood loss from drainage and application of elastic compression bandages.

摘要

血液节约共识会议使我们能够制定一些有趣的指导方针。自体输血和异体输血均需患者同意。对于血容量替代,放血低于10 - 15%时使用晶体溶液,放血超过血容量的10 - 15%时使用胶体溶液。严重等容血液稀释(血细胞比容<20%)时需要减少某些药物的剂量。在没有脑血管和冠状动脉疾病的情况下,放血后血红蛋白水平限制在9 g/dl左右可能是可以接受的。因此,当血红蛋白值为10 g/dl(血细胞比容30%)时也可以进行放血。术后晚期(第3至6天)血红蛋白值约为7 g/dl时,只有在耐受性良好的情况下才可以接受。手术期间及术后早期收集的血液必须始终进行离心、洗涤和微滤。随后,在最初8小时内,沉淀和微滤后的红细胞可以回输。预存式、血液稀释和回收技术是有效的,特别是与通过控制压力抽吸(最小负压,有时为正压)仔细控制术后出血、监测引流失血以及应用弹性压迫绷带相结合时。

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