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腹膜通气:实验性成人呼吸窘迫综合征肺外通气的动物模型

Peritoneal ventilation: an animal model of extrapulmonary ventilation in experimental adult respiratory distress syndrome.

作者信息

Barr J, Livne A, Lushkov G, Vinograd I, Efrati Y, Ballin A, Lahat E, Eshel G

机构信息

Pediatric Intensive Care Unit, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel.

出版信息

Pediatr Res. 1994 Jun;35(6):682-4. doi: 10.1203/00006450-199406000-00012.

DOI:10.1203/00006450-199406000-00012
PMID:7936818
Abstract

Adult respiratory distress syndrome (ARDS) is a critical medical problem in which severe arterial hypoxemia is often poorly responsive to conventional modes of mechanical ventilation. We studied the efficiency of mechanical ventilation of the peritoneal cavity in rabbits with experimental ARDS caused by lung lavage. The study shows that peritoneal ventilation is significantly effective in oxygenation of hypoxemic animals with ARDS and is also effective for carbon dioxide elimination. Peritoneal ventilation may be considered as an investigational method for extrapulmonary oxygenation in severe intractable hypoxemia caused by ARDS.

摘要

成人呼吸窘迫综合征(ARDS)是一个严重的医学问题,其中严重的动脉低氧血症对传统机械通气模式往往反应不佳。我们研究了在通过肺灌洗诱导实验性ARDS的兔中进行腹腔机械通气的效果。研究表明,腹腔通气对患有ARDS的低氧血症动物的氧合有显著效果,对二氧化碳清除也有效。腹腔通气可被视为一种用于治疗由ARDS导致的严重顽固性低氧血症的肺外氧合研究方法。

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Peritoneal ventilation: an animal model of extrapulmonary ventilation in experimental adult respiratory distress syndrome.腹膜通气:实验性成人呼吸窘迫综合征肺外通气的动物模型
Pediatr Res. 1994 Jun;35(6):682-4. doi: 10.1203/00006450-199406000-00012.
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Pumpless extracorporeal removal of carbon dioxide combined with ventilation using low tidal volume and high positive end-expiratory pressure in a patient with severe acute respiratory distress syndrome.在一名严重急性呼吸窘迫综合征患者中,采用低潮气量和高呼气末正压通气联合无泵体外二氧化碳清除技术。
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Adult respiratory distress syndrome treated with high-frequency positive pressure ventilation.高频正压通气治疗成人呼吸窘迫综合征。
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High-frequency percussive ventilation as a salvage modality in adult respiratory distress syndrome: a preliminary study.高频振荡通气作为成人呼吸窘迫综合征的一种挽救治疗方式:一项初步研究。
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[Comparative study of recruitment maneuver guided by pressure-volume curve on respiratory physiology and lung morphology between acute respiratory distress syndrome of pulmonary and extrapulmonary origin in canine models].犬模型中肺源性和肺外源性急性呼吸窘迫综合征压力-容积曲线引导下肺复张手法对呼吸生理和肺形态的比较研究
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引用本文的文献

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Exploring alternative routes for oxygen administration.探索氧气输送的替代途径。
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Systemic oxygen delivery by peritoneal perfusion of oxygen microbubbles.经腹腔内氧微泡灌注实现全身氧气输送。
Biomaterials. 2014 Mar;35(9):2600-6. doi: 10.1016/j.biomaterials.2013.12.070. Epub 2014 Jan 15.
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Peritoneal perfusion with oxygenated perfluorocarbon augments systemic oxygenation.用含氧全氟碳化合物进行腹腔灌注可增强全身氧合作用。
Chest. 2006 Aug;130(2):402-11. doi: 10.1378/chest.130.2.402.
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Peritoneal ventilation in rabbits: augmentation of gas exchange with cisapride.兔的腹膜通气:西沙必利增强气体交换
Thorax. 1996 Jan;51(1):82-6. doi: 10.1136/thx.51.1.82.